Medical doctor diploma (summa cum laude) from the University of Perugia (Italy); thesis on the role of calcium ion channels in the pathogenesis of asthma. Specialty diploma (summa cum laude) in pulmonary medicine and tisiology from the UniversitÓ Cattolica (Italy). Postgraduate research training at the UniversitÓ Cattolica (Italy) and at the McMaster University (Ontario, Canada).
Extensive clinical experience as board-certified pulmonologist, with over 18 years of specialty practice. Scientist with consolidated expertise in discovery research and in clinical and translational pulmonology. Entrepreneur with more than 20 years of working experience in the biopharmaceutical sector and a track record of success.
Founder of the International network for the Advancement of Viable Applicable Innovations in Life sciences (InAVAIL), which comprises R&D-performing and consulting organizations working to common aims and sharing innovative methodologies, data, infrastructures and resoures. Head of the associated discovery and preclinical research organization, the Avail Biomedical Research Institute (ABRI). Expert in Research & Innovation for the European Commission and other public research funding bodies. Eurostars-Eureka scientific and technical expert. Due diligence consultant for investment, acquisition or in-licensing opportunities in the biotechnology and pharmaceutical sectors. Formerly, contribution to the establishment of DreiRosen Pharma by technology development patnership and strategic advice, co-founder and scientific director of the university-affiliated research institution FIMS (Fondazione Italiana di Medicina Sperimentale). Previous experience in internationally accredited academic centers and in other pharmaceutical companies, with leadership positions combining scientific and medical specialty skills or requiring the ability to build multidisciplinary teams of experts for the conduction of translational or clinical research projects. Collaboration with academic institutions and various professional associations in the development of continuing education programs and training courses in pharmacology and pulmonary medicine.
Development of innovative approaches to major challenges in biomedical research and contribution to turn research results into market-creating innovations since the early nineties. Discovery of molecular and cellular pathways implicated in the pathogenesis of asthma. Identification of novel biomarkers of asthma severity and treatment outcome. Development of in-vitro and in-vivo models for the investigation of new therapeutic targets and for testing drug candidates. Invention of methods for producing stem cell-derived airway epithelial progenitor cells with regenerative potential. Isolation and characterization of stem cell-derived biologics with therapeutic potential in pulmonary fibroses and end-stage pulmonary diseases, which currently require lung transplantation. Setting up, growing and international expansions of businesses in the biopharmaceutical research and non-research commercial sectors. Effective collaboration with diverse start-ups and larger biopharmaceutical companies to accelerate the development and commercialization of 2 novel diagnostics and 8 therapeutic candidates. Contribution to the development of the first device for protection against the deleterious effects of inhaled pollutants (including allergens and cigarette smoke). Demonstration of the unreliability of available methods for monitoring and controlling air pollution at construction and demolition sites, with the in-progress research of innovative solutions.
Author of over 90 full-length articles published in peer-reviewed journals, including basic and clinical research articles, editorials and review papers. Author of 9 book chapters and more than 160 published conference abstracts. Consulting editor, member of the editorial board or ad-hoc referee for several scholarly journals.
International awards and honors have included a Top 10 Special Fellow-in-Training Award of the American Academy of Allergy and Immunology, a Medical Research Council of Canada Fellowship Award, the 1990 Pharmacia Allergy Research Foundation Honourable Mention for Progress in Research, and the 1990 Scientific Award for Excellence in Research of the XIII World Congress of Asthmology. In 1999, listed in the "Outstanding People of the 20th Century" for outstanding contribution to biomedical research, and biography inclusion in "Who's Who in the World", "Who's Who in Medicine and Healthcare" and "Who's Who in Finance and Industry". Recipient of the Top Reviewer Award for exceptional contribution to the quality of the Journal of Immunological Methods in the years 2009-2010. Invited speaker, in several scientific sections, symposia and postgraduate courses of international congresses organized by professional associations and major conference producers in the biomedical and pharmaceutical sectors, such as the American Thoracic Society, the British Thoracic Society, the European Tissue Repair Society, Oxford Global, and GTCbio.
View citations of my peer-reviewed full-length publications and the h-index in Scopus, Orcid and Web of Science
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